The W lab Holiday Party 2017
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The W Lab @ TempleOur lab aims to develop a multifaceted research program that leverages a unique class of hypervalent iodine reagents in novel approaches to heteroatom activation. Our research encompasses reagent development, new synthetic methods, and the application of these tools to the synthesis of natural products containing challenging medium-ring heterocycles. We aim to bridge the gap between the three-dimensional molecular complexity of nature and the planar aromatic structures of small molecule libraries by introducing simplified strategies and novel disconnections of these valuable architectures.
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W Lab News
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The Wengryniuk Lab has been awarded an NSF CAREER award!!! This award will support our adventures in the total synthesis of medium-ring ether natural products and umpolung C–H activation strategies. We are also so excited to launch some amazing outreach programs to mentor young women in science.
Thank you to the NSF for your support! |
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Breaking News and Events
Felipe and Brandon's paper entitled "Reactivity of (NNN)-pincer nickel(II) aryl complex towards oxidative carbon-heteroatom bond formation" has been accepted for publication in Tetrahedron in a Special Issue honoring Prof. Seth Herzon's Young Investigator Award (Accepted Article: https://doi.org/10.1016/j.tet.2018.04.029). Great work from Felipe and Brandon, and congratulations to Seth on a well deserved honor!
Jen, Tony and Aimee's paper on the ring expansion of aliphatic secondary alcohols with N-HVIs has been accepted to Eur. J. Org. Chem. DOI: 10.1002/ejoc.201800118. Not only does this method provide rapid access to challenging medium-ring oxygen heterocycles, but is applicable to the late-stage derivatization of complex natural product scaffolds, providing new opportunities in Complexity-to-Diversity pursuits. Be sure to check out the product of their great work! Congrats team!
Congrats to rock star W lab undergrads Maria Velopolcek and Nate Greenwood on both securing internships in medicinal chemistry at BMS this summer! Thank you to BMS for creating such an awesome intern program and giving them this opportunity.
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